NUR 3123 Pathophysiology and Pharmacology
COURSE DESCRIPTION
This course is designed to improve the learner’s ability to understand cellular physiology and alterations in structure and function resulting from the action of stressors on the human body at the cellular level. Physiological, pathophysiological, psychobiological, and pharmacological concepts are examined that provide a foundation for understanding the pathophysiology of disease and the rationale for treatment including pharmacologic therapy that serves as a basis for critical thinking and decision making in the planning and managing of care for individuals across the life span are examined.
COURSE OBJECTIVES
Upon completion of this course, the student will be able to:
1) Utilize principles from the biological and behavioral sciences to understand pathophysiological and psychobiological processes across the lifespan.
2) Explain relationships among pathophysiological processes, laboratory and diagnostic tests, and clinical manifestations of selected illnesses and pharmacological treatment.
3) Identify genetic factors that influence pathophysiological and psychobiological processes in diverse clients.
4) Distinguish differences between developmental physiological alterations and pathophysiological processes.
5) Explain psychobiological processes associated with functional alterations in the client’s behavior.
Explain the rationale for pharmacological therapies related to the physiological, pathophysiological, and/or psychobiological processes occurring in the individual.
TOPICAL OUTLINE
1) Cellular metabolism and genetic basis of health
2) Fluid and electrolytes
3) Acid/base balance
4) Alterations in physiological systems
5) Hematopoietic system
6) Immune system
7) Cellular proliferation
9) Pulmonary system
10) Digestive system
11) Endocrine system
12) Renal system
13) Reproductive systems
14) Neurological system
15) Musculoskeletal system
16) Integumentary system
17) Alterations in cognition, perception and effect
TEACHING METHODS
Lecture, audiovisual materials, written materials, and presentation of case studies.
LEARNING ACTIVITIES
Readings, worksheets, discussions, case study analysis, and study questions.
WEEKLY CLASS SCHEDULE
| DATE | PATHOPHYSIOLOGY
TOPIC/EVALUATION |
PATHOPHYSIOLOGY
ASSIGNMENTS/READINGS |
PHARMACOLOGY
TOPIC/EVALUATION |
PHARMACOLOGY
ASSIGNMENTS/READINGS |
| Week 1
May 14-20 |
Introduction, Cellular Metabolism, Stress | McCance: pp. 25-28, Chapters 2, 7, 11, 16, & pp. 1668-1679.
Syll. Quiz Due 5/20, 11:59pm Quiz #1 Due by 5/20, 11:59pm |
Introduction | Burchum (B):
Unit 1 – Ch. 1, 2, 3 Elsevier (E): Unit 1 Canvas (C): Lecture Pharmacology Discussion #1 Due by 5/20, 11:59 pm (post to other students by 5/23, 11:59 pm) |
| Week 2
May 21-27 |
Fluids & Electrolytes
Acids & Bases |
McCance: Chapter 3
Quiz #2 Due by 5/27, 11:59pm |
Basic Principles of Pharmacology
· Pharmacokinetics · Pharmacodynamics |
B: Unit II (Ch. 4, 5)
E: Unit II C: Lecture Pharmacology Quiz #1 Due by 5/27, 11:59 pm |
| Week 3
May 28 – June 3 |
Hematopoietic System | McCance: Chapters 27, 28, 29 & pp. 1063-1068
Quiz #3 Due by 6/3, 11:59pm |
Basic Principles of Pharmacology
· Drug Interactions · Adverse Reactions · Medication Errors · Individual Drug Responses |
B: Unit II (Ch. 6, 7, 8)
E: Unit II C: Lecture
Pharmacology Quiz #2 Due by 6/3, 11:59pm |
| Week 4
June 4-10 |
Immune System
Exam 1: Proctor U June 5 or 6 |
McCance: Chapters 7, 8, 9, & 10
Quiz #4 Due by 6/10, 11:59pm |
Antiinflammatory, Antiallergic, and Immunologic Drugs | B: Unit XI (Ch. 67, 68, 69, 70, 71, 72)
E: Unit XI C: Lecture |
| Week 5
June 11-17 |
Cancer | McCance: Chapters 12, 13, & pp. 1013-1035
Quiz #5 Due by 6/17, 11:59pm
|
Cancer Chemotherapy | B: Unit XVIII (Ch. 101, 102, 103)
E: Unit XVIII C: Lecture |
| Week 6
June 18-24 |
Pulmonary System | McCance: Chapters 34, 35, &
pp. 1310-1312
Quiz #6 Due by 6/24, 11:59pm
|
Respiratory Tract Drugs | B: Unit XIII (Ch. 76, 77)
E: Unit XIII C: Lecture Pharmacology Quiz #3 Due by 6/24, 11:59pm
|
| June 25-29
|
Summer Break | |||
| Week 7
July 2-8 |
Cardiovascular System | McCance: Chapters 31 & 32
Quiz #7 Due by 7/8, 11:59pm |
Drugs that Affect the Heart, Blood Vessels, and Blood | B: Unit VII (Ch. 43, 44, 45, 46, 47)
E: Unit VII C: Lecture Pharmacology Discussion #2 Due by 7/8, 11:59 pm (post to other students by 7/11, 11:59 pm)
|
| Week 8
July 9-15 |
Urinary, Renal, & Reproductive Systems
Exam 2: Proctor U July 11 or July 12 |
McCance: Chapters 37, 38, &
pp. 850-871
Quiz #8 Due by 7/15, 11:59pm |
Chemotherapy of Infectious Diseases | B: Unit XVI (Ch. 83); Recommend Review Chapters: 84-96
E: Unit XVI C: Lecture Pharmacology Quiz #4 Due to 7/15, 11:59 pm
|
| Week 9
July 16-22 |
Gastrointestinal System | McCance: Chapters 40 & 41
Quiz #9 Due by 7/22, 11:59pm
|
Gastrointestinal Drugs | B: Unit XIV (Ch. 78, 79, 80)
E: Unit XIV C: Lecture Pharmacology Quiz #5 Due by 7/22, 11:59pm
|
| Week 10
July 23-29 |
Endocrine System
Musculoskeletal System |
McCance: Chapter 22, 43, & 44
Quiz #10 Due 7/29, 11:59pm |
Drugs for Endocrine Disorders | B: Unit VIII (Ch. 57, 58, 59, 60)
E: Unit VIII C: Lecture Pharmacology Discussion #3 Due by 7/29, 11:59 pm (post to other students by 8/1, 11:59 pm)
|
| Week 11
July 30 – August 5 |
Neurologic System
Case Study: Due August 1, 2359PM |
McCance: Chapters 17 & 18
Quiz #11 Due 8/5, 11:59pm |
· Drug Therapy Across the Life Span
· Peripheral Nervous System Drugs · Central Nervous System Drugs |
B: Unit III (Ch. 9, 10, 11)
Unit IV (Ch. 12, 13) Unit V (Ch. 20) E: Unit III Unit IV Unit V C: Lecture Quiz #6 Due by 8/5, 11:59pm
|
| Week 12
August 6-10
|
Exam 3: Proctor U August 6 or August 7 |
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